The computer supplied with the labchip gx instrument has internal. Caliper labchi p gx instruments contain class 3b laser diodes. Improving the efficiency of metagenomic analysis of stool samples 2018 automated ngs library preparation with covaris focusedultrasonicator workflow solution 2018 labchip gx touch platform applications in epigenetic studies. This includes access security, data security and verification, and a complete set of audit logging. Like its predecessor the labchip90, the gx suite of instruments utilizes perkinelmers innovative microfluidics technology to perform reproducible, highresolution, eletrophoretic separations. Genomic analysis of samples is performed with either labchip consumable cls8948 labchip gx touch 24 system or 760517 labchip gx touch ht system and delivers accurate, reproducible results rapidly.
That further emphasizes the importance of monitoring fucosylation during development and manufacturing of relevant therapeutic antibodies, including during culture media development and optimization. After connecting a pc and opening the labchip software. Labchip gx touch nucleic acid analyzer perkinelmer. Electrical safety the labchip gx is powered by a ulcsavde approved 100240 vac, 5060 hz input, 5, 15, 24 vdc output power supply. Access genetics will incorporate webbased software, materials, and protocols that the company developed specifically for use with labchip gx. Labchip gx instruments contain class 3b laser diodes.
The labchip gxii touch system quantifies protein attributes from process development through quality control in biotherapeutics development and manufacturing. The labchip gx system provides laboratories offering. Operation and maintenance of the labchipgx for rna samples using the. Operation is subject to the following two conditions. Product note rapid, costeffective oil condition monitoring spectrum oilexpress system. Liquid handling applications development from perkinelmer duration.
White paper streamlining materials innovation processes with electronic lab notebook eln and data analytics for optimum efficiency. Labchip gx touch microfluidics capillary electrophoresis. The labchip gx is classified as a class 1 device because the lasers are appropriately enclosed embedded and indicated with warning labels. When speed, accuracy and easeofuse are paramount, the labchip gx is the perfect solution. May 26, 2016 labchip gx touch microfluidics for dnarna analysis duration. With the development of the caliper gx ii, a highthroughput microfluidicsbased platform, 96 samples can be processed in 2. Then, will be discussed application on mce that have been developed to address those. The labchip gx software displays the raw data as an electropherogram and generates a gellike image for visualization, data such as peak heights, peak areas, concentration, etc. This device may not cause harmful interference, and. Dna and rna quantitation and sizing can be done in seconds using automated capillary electrophoresis separation.
Additionally it provides data in tabular form, which can then be analyzed or easily exported into a spreadsheet format. Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. The efficient production of these nutritionally fortified breakfast cereals requires careful formulation and uniformity batch to batch. The labchip gx is the most accurate and advanced nucleic acid separations system available. In addition to the instrument, the complete system also includes the labchip gx software for data analysis. Labchip gxii touch ht protein characterization system. Fast separation time less than 60 seconds per sample software determines the relative amounts of glycans present up to. Labchip gx touchgx touch ii user manual perkinelmer. Ssm program, the joap program, and the new astm methods d7412, d7414, d7415, d7418, spectrum oilexpress is the fastest, most costeffective oil condition monitoring ocm solution for busy test laboratories. Ongoing analytical measurement of nutritional additives and the total micronutrient content in the cereal is one way in which food producers can quantify the quality and consistency of their cereal products. These results demonstrate that the labchip gx touch platform offers a high level of resolution that allows for. The information in this section is from caliper labchip gxgx ii user manual how the caliper software analyzes rna data. The labchip gx is designed for both rna and dna analysis, while the labchip gxii runs rna, dna, and also protein assays.
Using a curve comparing the theoretical and given concentrations, the intercept of the curve has been assigned to the background titer y0. Right click on the link to the file and choose save target as and save the zip file to your desktop. Comparison of agilent 2100 bioanalyzer and caliper life. Labchip gx touch nucleic acid analyzer library perkinelmer. Read our library of application notes and flyers to learn more about the labchip gx touch nucleic acid analyzer. Education software downloads perkinelmer chemdraw professional by perkinelmer informatics, inc. Labchip gxii touch reducing time to result for protein characterization automated electrophoretic separations of rna, dna, proteins and glycans capillary electrophoresis performed in microfluidic chips sample directly from 96 or 384well microtiter plate comprehensive and quantitative analysis with labchip gx software. Selexis sa, 14 chemin des aulx, ch1228 plan les ouates. In this study, the agilent 2100 bioanalyzer and the caliper gx ii have been evaluated to compare total rna scoring algorithms, reproducibility, and the ability to provide informative rna quality metrics to help in. This labchip gx system has been inspected and tested by our technician to ensure. Data analysis utilizing empower and labchip gx software. Log on to nimbus and start the hamilton run control software.
Labchip gx touch nucleic acid analyzer perkinelmer applied. Apr, 2010 access genetics will incorporate webbased software, materials, and protocols that the company developed specifically for use with labchip gx. Rapid analysis of nglycans on the labchip gxii microchipce. Rapid analysis of nglycans on the labchip gxii microchipce platform. Caliper labchip gx automated electrophoresis rna dna. Relative percentages of major molecular species and charge variants were quantified with labchip gx software. Labchip gxii touch ht protein characterization system at. Labchip gxii touch biotherapeutics how a chip works. The software lies within education tools, more precisely science tools. Whether analyzing rna integrity for better gene expression data or assessing pcr fragments for resequencing applications, the labchip gx instrument accelerates your research and helps you generate more meaningful data, faster. Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of glpcompliant processes in the worlds leading pharmaceutical, biotechnology and contract research organizations.
Screening nucleic acid source material for sarscov2 vaccine development. Ngs library preparation smear and fragment analysis and quality control rna and dna fragment analysis including cellfree dna, dna isolated from ffpe samples, and pcrfree libraries. A long history in transplant medicine and now the era of regenerative medicine. Caliper labchip gx automated electrophoresis rna dna analysis. Labchip gx touch microfluidics for dnarna analysis youtube. The labchip gx software can open multiple data files in the same workspace to compare the data from different plates. It allows the complete assessment of rna quality for better gene expression data. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible, highresolution data and is optimal for. Fcc this device complies with part 15 of the fcc united states federal communications commission rules. The labchip gxii touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. The system can be located in a designated laboratory room to limit system access to authorized individuals 21 cfr 11.
The software contains an application security module for user account management and for access of controls to. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible, highresolution data and is optimal for ngs library preparation smear and fragment analysis and quality control. Our antivirus scan shows that this download is clean. Part of the labchip training video series if you have any questions after watching this video, please contact technical support. Used labchip software to connect pc to labchip gx system. Leveraging microfluidic electrophoretic separation technology, the labchip gxii touch system enables rapid characterization with minimal sample. Integrates the celif process onto a microfluidic chip reagents provided in 96well plate format for convenience and ease of automation automatic sampling from a 96well plate fast separation time less than 60 seconds per sample.
Labchip gx touch platform applications in epigenetic studies. Contact the perkinelmer center for training and development for information. Designed specifically to meet the requirements of the caterpillar s. Labchip gxii touch biotherapeutics how a chip works youtube. Labchip gx microchip electrophoresis system key features. The labchip gxgxii electrophoresis systems use a single sipper microfluidic chip to aspirate samples directly from 96 or 384well plates. Coordinated feature definition and software development for ten lumina ii, lumina xr, kinetic, spectrum, labchip xt, labchip gx, labchip dx, ezr, ezt, lc3000 different systems with four. Leveraging microfluidic electrophoretic separation technology, the labchip gxii touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
The labchip gxgxii systems offer researchers an automated alternative by streamlining the multiple, manual steps of slab gel electrophoresis, while also providing the throughput and data quality essential for life science laboratories today. When powered on, the chip, eject, and status indicators labchip gxii light up. This paper explores the numerous challenges materials scientists and engineers face, from the time it takes to bring new materials to market to the difficulties delivering suitable formulations and testing against specified criteria, and how those can be resolved. Labchip gx rna, dna, and protein analysis software import labchip gx or labchip 90 data files with ease labchip gx allows users to compare data from several different sample plates.
Labchip gx touch microfluidics capillary electrophoresis by. Mackenzie poskus lesley university greater boston area. The labchip gxgxii systems offer researchers an automated alternative by streamlining the multiple, manual steps of slab gel electrophoresis. Labchip gx is a program that provides support for the high sensitivity dnarna analysis, dna smear analysis, rna and gdna integrity. Perkinelmer has led the way for over 25 years with powerful software and informatics solutions. Antibody analysis using calipers labchip gxii system.
The actual developer of the free software is perkinelmer inc. Antibody analysis using calipers labchip gxii system abstract current initiatives in process analytical technology pat and quality by design qbd are driving the need to identify and thoroughly understand the relation between critical process parameters cpp and critical quality attributes cqas1. When prompted by the nimbus program heat denature, chill and spin down. A caliper labchip gxgxii instrument with labchip gxp software is a closed system 21 cfr 11. Labchip gx touch data analysis software allows users to visualize results via an electropherogram or virtual gel view. Apr 12, 2016 according to the manufacturers recommendation, we purified antibody samples using reagents from the kit at ph 6. The instrument optics detect samples by laserinduced fluorescence. Additionally, the labchip gx high voltage circuitry is currentlimited to nonhazardous levels. This was tested on the labchip gx instrument, which detects the alexa660 fluorophore, and we observed that halotag fusion proteins can be assessed specifically and in parallel with the standard measurements of total protein.
B labchip gx touch gxii touch user manual perkinelmer, inc. The new systems, the labchip gx and labchip gxii have been designed to replace the widely adopted labchip 90 and combine calipers robust separation and assay technologies with higher throughput, extended walk away time and more economical plate processing. To provide guidelines for operating and maintaining the caliper labchip gx and for running the. Access genetics to offer calipers labchip gx as molecular.
Use the links below to quickly find your software solution download. Perkinelmer launches labchip gx touch and gxii touchtm. The labchip gx touch system provides rapid, quantifiable data for pre and postpcr sample analysis, which is critical for nextgeneration sequencing and genomics workflows. The labchip gx rna assay analysis determines the quality of the rna sample by measuring the relative amounts of know rna fragments relative to the total rna present in the sample. Lcf4524 teaching utility is now available in nondeveloper mode. System requirements for labchip gx software instrument mode labchip gx. The virtual gel image presented in figure 4 shows the fragment size results for three melanoma samples.
Labchip gx is a program that provides support for the high sensitivity dnarna analysis, dna smear analysis, rna and gdna integrity analysis. The labchip gx software can open multiple data files in. With sample acquisition time under 40 seconds the instrument can thoroughly analyze 96 protein samples in less than an hour, virtually eliminating throughput bottlenecks and improving efficiency. The labchip gxii touch protein characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and genomics workflows. This kit should be used in conjunction with a labchip gx touch instrument, and is used for dna ranging from 1005,000 basepairs in size. It uses an intuitive interface to guide users through protocol selection and deck setup, as well as, displays inrun status and details. Rapid analysis of nglycans on the labchip gxii microchip.
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